PCOS and Endometrial Cancer: Understanding the Risks

by Indra on August 1, 2023 , 6 min read

Polycystic Ovary Syndrome (PCOS) is a prevalent hormonal disorder that affects many women worldwide. Beyond its well-known impact on fertility and menstrual irregularities, PCOS is also associated with an increased risk of developing endometrial cancer. Understanding the connection between PCOS and endometrial cancer is vital for women with this condition. In this comprehensive guide, we will delve into the role of PCOS in endometrial cancer, the risks involved, and effective strategies to reduce the risk if you have PCOS.


The Role of PCOS in Endometrial Cancer

PCOS is characterized by hormonal imbalances in the body, leading to the development of small cysts in the ovaries. These hormonal imbalances, particularly elevated levels of oestrogen, can have a significant impact on the endometrium—the lining of the uterus—increasing the risk of endometrial cancer.


PCOS as a Risk Factor

  1. Hormone Imbalance in PCOS: In PCOS, the ovaries produce excessive amounts of oestrogen compared to progesterone. This hormonal imbalance can lead to the overgrowth of the endometrium, a condition known as endometrial hyperplasia. If left untreated, endometrial hyperplasia can progress to endometrial cancer.

  2. PCOS and Endometrial Hyperplasia: Endometrial hyperplasia is a condition characterized by the thickening of the endometrium due to increased oestrogen levels. Women with PCOS are at a higher risk of developing endometrial hyperplasia, which, in turn, increases the likelihood of endometrial cancer.


How Endometrial Cancer is Diagnosed and Treated

Early detection and proper treatment are crucial to managing endometrial cancer. The following methods are commonly used for diagnosis and treatment:



  • Diagnosis: Endometrial cancer is diagnosed through various techniques, including pelvic exams, ultrasound, endometrial biopsy, and imaging tests. These procedures help identify any abnormalities or cancerous growths in the endometrium.

  • Treatment: The treatment options for endometrial cancer depend on several factors, including the stage and severity of the cancer. Common treatment approaches include surgery, radiation therapy, chemotherapy, and hormone therapy. The choice of treatment is determined by a healthcare professional based on individual circumstances.


How to Reduce the Risk of Endometrial Cancer if You Have PCOS

If you have PCOS, there are several proactive steps you can take to reduce the risk of developing endometrial cancer. Here are some effective strategies:



  1. Treat Your PCOS: Managing PCOS through lifestyle changes, medication to regulate hormones, and regular medical check-ups is essential. Working with a healthcare professional, such as a gynaecologist or endocrinologist, can help regulate hormone levels and minimize the associated risks.

  2. Reach and Maintain a Healthy Body Weight: Maintaining a healthy body weight is crucial to managing PCOS and reducing the risk of endometrial cancer. Excess body fat can lead to increased oestrogen production, further contributing to hormonal imbalances. Incorporate a balanced diet and regular physical activity to achieve and maintain a healthy weight.

  3. Avoid Fats in Your Diet: Limiting the intake of unhealthy fats, such as saturated and trans fats, is beneficial for overall health and PCOS management. Focus on consuming a diet rich in fruits, vegetables, whole grains, lean proteins, and healthy fats like those found in nuts, seeds, and fatty fish.

  4. Get Frequent Pap Smears and Pelvic Exams: Regular check-ups, including Pap smears and pelvic exams, are essential for early detection of any abnormalities in the cervix or uterus. These screenings can help identify any signs of endometrial changes or potential cancerous growths, enabling timely intervention and treatment.

  5. Stay Active and Exercise Regularly: Engaging in regular physical activity not only helps with weight management but also improves overall health and reduces the risk of endometrial cancer. Aim for at least 150 minutes of moderate-intensity aerobic exercise per week, along with strength-training exercises.

  6. Manage Stress Levels: Chronic stress can contribute to hormonal imbalances and negatively impact overall health. Find healthy ways to manage stress, such as practicing relaxation techniques, engaging in hobbies, and seeking support from loved ones.

  7. Stay Educated and Advocate for yourself. Stay informed about the latest research and developments regarding PCOS and endometrial cancer. Advocate for yourself by seeking the guidance of knowledgeable healthcare professionals, joining support groups, and actively participating in your own healthcare decisions.


Does Sperm Count Affect IVF Success?

While this guide primarily focuses on PCOS and endometrial cancer, it's worth mentioning that male fertility, including sperm count and quality, can also affect the success of assisted reproductive techniques such as In Vitro Fertilization (IVF). If you and your partner are considering IVF, it is essential to address any potential male fertility issues and consult with a fertility specialist for a comprehensive evaluation and personalized guidance.


When to See a Doctor

If you have PCOS and are concerned about the potential risks of endometrial cancer, it is advisable to consult with a healthcare professional specializing in reproductive health. They can assess your specific situation, provide appropriate guidance, and monitor your health regularly to ensure early detection and effective management.




Understanding the risks associated with PCOS and endometrial cancer is crucial for women with this condition. By addressing hormonal imbalances, managing PCOS through appropriate treatment, adopting a healthy lifestyle, receiving regular medical check-ups, and staying informed, you can reduce the risk of developing endometrial cancer. To reduce the risk of endometrial cancer, managing PCOS effectively is crucial. Seeking PCOS And PCOD Treatment through a gynaecologist's online consultation can provide personalized guidance and treatment options tailored to individual needs. In addition to medical intervention, considering PCOS supplements can complement the treatment plan and support hormone regulation.

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by Indra on August 1, 2023 , 6 min read

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